The medical device industry has become more focused on providing people in rural areas of sub-Saharan Africa with access to cost-effective, easy-to-manufacture solutions. The combination of healthcare challenges, and advancements in technology, have influenced the transition in the medical device industry and led to the development of new products that solve unique African challenges. As such, African companies have developed ground-breaking ideas, shaped in response to the region’s challenging social economic conditions, to address the medical needs of the continent. Organisations like Himore Medical, Aviro Health, and Deftronics are at the forefront of this boom in innovation and demonstrate the potential for newly technological advancements that can easily be adapted to other regions across the world.